Low Testosterone: A Marker for Heart Disease?

Profile trials conducted and published in recent years have shown that there is a link between testosterone levels and reduce the occurrence of medical conditions. A study published in 2006 showed that of the 2,100 men included in the study (aged over 45), the chances were that testosterone is reduced:

– 2.4 times higher in obese men;

– 2.1 times higher in men with diabetes;

– 1.8 times higher in men with hypertension;diabetes

Experts in the field will not incriminate decreased testosterone for the occurrence of these problems. In fact, there are increased chances that even if things actually stand opposite: these chronic conditions affect how the body secretes testosterone. So under such circumstances it can be said that the decline in testosterone may be a marker that something is wrong in the body, that somewhere there is illness. Given this observation, experts believe it is worth investigating this possibility, which is why many are currently ongoing studies investigating the link between chronic heart disease and testosterone.

Cardiovascular disease and testosterone levels

Testosterone has a mixed effect on arteries. It seems it adjusts certain receptors on the surface of platelets and thus stimulates platelet aggregation, causing thrombus formation. Some experts believe that increased testosterone levels over time can damage heart health, influencing and accelerating the occurrence of hypertension, even in young men.

On the other hand, testosterone deficiency correlates, as  mentioned, to obesity, metabolic syndrome and diabetes, all of which counting are actually among the most dangerous and important risk factors for cardiovascular problems. Men with such conditions may suffer a atherosclerosis on a much larger and faster pace (plaque progressing rapidly and significantly reducing the vascular lumen functional until even reach critical values), which will further increase the risk of thrombotic events.

Testosterone, in the normal amount, could improve the global health of arteries because it is metabolically turned into estrogen, which promotes artery functionality. There are currently no clinical trials to assert that administration of testosterone replacement therapy is beneficially influencing arteries or significantly reduces the risk of atherosclerosis, coronary events and strokes.